CRISPR
The first CRISPR therapy approved in the U.S. will treat sickle cell disease
U.S. patients with sickle cell disease now have a novel treatment option: the first-ever CRISPR-based therapy. On December 8, the U.S. Food and Drug Administration approved the gene-editing therapy for use in patients age 12 years and older. In addition to offering hope of relief for people with severe forms of the painful blood disorder,…
Jennifer Doudna Believes Crispr Is for Everyone
It’s been a monumental year for Crispr, the molecular tool scientists use to edit genetic material. This November, the United Kingdom authorized the first medical treatment using Crispr gene editing, giving people with sickle cell disease new opportunities to receive a one-time therapy to prevent episodes of terrible pain. This week, the US Food and…
The First Crispr Medicine Is Now Approved in the US
Casgevy uses the Nobel Prize–winning technology Crispr to modify patients’ cells so that they produce healthy hemoglobin instead. The Crispr system has two parts: a protein that cuts genetic material and a guide molecule that tells it where in the genome to make the cut. To do this, a patient’s stem cells are taken out…
Search algorithm reveals nearly 200 new kinds of CRISPR systems | MIT News
Microbial sequence databases contain a wealth of information about enzymes and other molecules that could be adapted for biotechnology. But these databases have grown so large in recent years that they’ve become difficult to search efficiently for enzymes of interest. Now, scientists at the McGovern Institute for Brain Research at MIT, the Broad Institute of…