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A new computational technique could make it easier to engineer useful proteins | MIT News

To engineer proteins with useful functions, researchers usually begin with a natural protein that has a desirable function, such as emitting fluorescent light, and put it through many rounds of random mutation that eventually generate an optimized version of the protein. This process has yielded optimized versions of many important proteins, including green fluorescent protein…

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Technique could efficiently solve partial differential equations for numerous applications | MIT News

In fields such as physics and engineering, partial differential equations (PDEs) are used to model complex physical processes to generate insight into how some of the most complicated physical and natural systems in the world function. To solve these difficult equations, researchers use high-fidelity numerical solvers, which can be very time-consuming and computationally expensive to…

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A gene editing technique shows promise for lowering LDL cholesterol 

PHILADELPHIA ­— Ten patients enrolled in the experimental drug trial, and they were the sickest of the sick.  All had a genetic disorder that cranks up levels of LDL cholesterol in the blood. Known as “bad cholesterol,” LDL cholesterol is infamous for clogging arteries. The patients’ disorder, called heterozygous familial hypercholesterolemia, can lead to severe heart…

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A pose-mapping technique could remotely evaluate patients with cerebral palsy | MIT News

It can be a hassle to get to the doctor’s office. And the task can be especially challenging for parents of children with motor disorders such as cerebral palsy, as a clinician must evaluate the child in person on a regular basis, often for an hour at a time. Making it to these frequent evaluations…

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New technique helps robots pack objects into a tight space | MIT News

Anyone who has ever tried to pack a family-sized amount of luggage into a sedan-sized trunk knows this is a hard problem. Robots struggle with dense packing tasks, too. For the robot, solving the packing problem involves satisfying many constraints, such as stacking luggage so suitcases don’t topple out of the trunk, heavy objects aren’t…

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Technique enables AI on edge devices to keep learning over time | MIT News

Personalized deep-learning models can enable artificial intelligence chatbots that adapt to understand a user’s accent or smart keyboards that continuously update to better predict the next word based on someone’s typing history. This customization requires constant fine-tuning of a machine-learning model with new data. Because smartphones and other edge devices lack the memory and computational…

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